A Breakthrough in Skin Care
The Benefits of Phytoceramides
Are you worried about the aging process and the visible signs of skin deterioration? Are you self conscious of the new spots, wrinkles, and loss of firmness that keep increasing each year?
The aging process is one fact of life that we all wish we could slow down. You may wonder is there a safe, natural and painless way to help you skin age gracefully and beautifully that doesn’t cost you thousands? The answer is YES!
You will often read about ‘miracle’ anti-aging supplements, and sadly you will find that most have no science or research to back up their claims, and few happy customers. However, enter the power of plants! There is one plant-derived molecule, Phytoceramides, that has made people sit up and take notice thanks to its impressive results: Phytoceramide rich Skin Zen may just be the answer that we have all been looking for.
Before we get in-depth about Phytoceramides, what they are and how they work, consider this: These plant molecules have been endorsed by some of the highest-profile stars in the world of film and television. Ellen DeGeneres, Cindy Crawford, and Jennifer Aniston are just a few of the celebrities who have admitted to using Phytoceramides to get the beautiful smooth skin they require. Dr Oz even talked about their benefits and the science behind how it works and had this to say about the product:
“What Phytoceramides do is get rid of all the old, dead layers of skin and help your skin generate fresh new ones. They move up from the younger skin, to the older skin from the inside out. They bind the skin together and make your skin plumper. The water doesn’t escape as much, you get less cracking, and the wrinkles go away! Even the dryness is less obvious. Our tests show that you can erase almost 20 years off your face in less than 14 days.”
The good news, is you don’t have to be a superstar to reap the benefits of this supplement. And we know you may be thinking “this HAS To be too good to be true”, but stay with us, and let’s look into the science.
Phytoceramides are being called the new Botox alternative, and it’s really important to know why this is a substantially safer choice.
While most consumers are told Botox is completely safe, the real research and anecdotal reviews show otherwise. Botox can lead to numerous, life-altering effects including Central Nervous System Toxicity. It is a known neurotoxin which can cause serious long term effects on brain function among many other things.
With over $1 billion dollars spent each year on Botox alone thanks to the nearly 3 million people who use it regularly, it’s easy to see why the truth of this product stays so well hidden. Since Botox comes with a hefty price tag and serious health risks that you won’t see talked about in most Dr’s offices, a natural supplement that can provide the same results is certainly going to disrupt the industry.
Phytoceramides, which is an FDA approved dietary supplement, are shocking dermatologists all around the world and for good reason. The studies on this supplement done at Osaka City University, which requires no prescription, have shown how easily you can turn back time in regards to aging skin making it the perfect alternative to other more dangerous options. Safer, cheaper and no needles or surgery scissors needed = win, win, win.
So What Exactly Are Phytoceramides?
It is important that we understand what Ceramides, which make up a good portion of the constituent of Phytoceramides, are: Ceramides are known as lipids, and they are the essential elements that make up most of the outer layer of the skin. They are there for protection, and also help keep the skin hydrated. Initially, research was focused on identifying potentially useful benefits of ceramides only from animal sources. Then scientists switched to using a number of different ceramides available in plants. These plant-based ceramides are called phytoceramides.
Your Skin’s Natural Regeneration Molecules
One essential role of ceramides is in the maintenance of water-retaining properties of the skin which keeps the skin supple and protects from damage and aging.
As you age, your skin progressively loses these natural lipids, resulting is visible aging that includes wrinkles, age spots, and rough, uneven skin. Ceramides are major skin components that help form the “glue” that holds surface cells together. Depletion of these molecules not only causes skin to wrinkle, but also makes it more susceptible to moisture loss, environmental allergens, skin diseases such as dermatitis, and possibly cancer. Ceramides, an important substance that not only helps protect against damaging pollution but also keeps us shielded from the harmful UV rays of the sun.
Although ceramides are present in many of the foods we eat, including rice and wheat, they do not naturally occur in sufficient quantities to optimally rejuvenate aging skin. This means that slowing and reversing skin aging requires effective supplementation.
How does it work and what can I expect?
Like many such products Phytoceramides consists of a set of strong antioxidants; these work to reduce the free radicals, which damage the skin, to reduce the aging process. In the case of Phytoceramides, the effect is to increase the amount of collagen and elastin that the body naturally produces, which is what keep the skin young and wrinkle-free for longer. Elastin is essential for ensuring that your skin remains in a healthy and young state, while collagen is there to keep it firm, which reduces the marks and wrinkles that come with aging. Studies also show phytoceramides inhibit elastase enzymes, which would ordinarily destroy elastin and contribute to loss of skin flexibility and increased wrinkling. However, these amazing benefits are only part of the equation.
Phytoceramides also work by keeping the skin moisturized to a degree that enables it to remain in a healthy state; Skin Zen also includes a number of essential and worthwhile vitamins, designed to work synergistically with the process. This complete formula is a perfect tool to help you combat the aging process and to stay looking healthy and young for as long as you can.
Lastly, ceramides have additionally been shown to inhibit melanogenesis, the process by which the skin produces the hyperpigmentation behind age spots and other discolorations of the skin. This suggests that by replacing ceramides from the inside out, with phytoceramides may inhibit or reverse the uneven pigmentation of skin aging.
Skin Zen has been scientifically shown to aid in
– Removing lines and wrinkles on the skin
– Hydrating the skin and keeping it healthy and youthful
– Reducing age spots
– Removing bags under the eyes
– Firming up the facial skin
– Protecting against UV rays and pollutants
These results are Validated In Clinical Trials. To demonstrate phytoceramides’ effectiveness, investigators conducted experiments of the scientifically most rigorous type: double-blind, placebo-controlled, clinical studies. See references below.
There are many products that make wild claims to achieve some of the above, yet Phytoceramides have been approved by the FDA and are promoted for use by many prestigious surgeons and skin care specialists who have found the results to be above satisfactory.
How Do You Take Phytoceramides?
So now that we know what Phytoceramides are and how they work, how do you use them?
Skin Zen, unlike most skincare protocols is not applied topically. It helps attack the aging process internally and our capsule delivery could not be easier! Oral phytoceramides effectively work from the inside out to hydrate, smooth, and rejuvenate aging and wrinkled skin from the inside out.
Ceramides have long been added to expensive skin care creams but this method falls incredibly short when it comes to effects. Researchers have discovered that adding ceramides directly to the skin can improve the moisture barrier function-but only modestly. The problem is that a topical ceramide application is not the body’s natural route for infusing the skin’s outer layer with ceramide molecules. That’s why creams and lotions, applied to the outer surface of the skin do not penetrate deeply enough into the skin to effectively block wrinkle formation and skin aging.
Fortunately we have developed phytoceramides that can be taken internally, ensuring that these potent molecules are absorbed into the bloodstream. This delivery has been shown in tests to be 20 times more effective than other products that are applied topically. Once absorbed, they are carried to the cells of the inner layer of the skin and subsequently seep to the outermost layer. The best part about oral delivery is these rejuvenating molecules reach skin all over the body, not just where a cream is applied. And really, who doesn’t want beautiful, firm skin EVERYWHERE on their body?
Many users report changes in the way their skin looks and feels within a week; some have even said that they have felt a difference in a matter of a day or two. This is because Skin Zen gives the skin back what has been lost naturally. You will soon notice a reduction in lines and dark spots on the skin, and around four weeks the difference will be very noticeable.
Rigorous clinical studies show that oral phytoceramides increase skin hydration, smoothness, suppleness, and other measures of youthful skin.
Ceramides are a natural substance found in your skin. But over time, the amount of ceramides dwindle away. This leads to drier skin, wrinkling, age spots and sagging. Phytoceramides are an extremely powerful antioxidant found in certain plants. They replenish your ceramides, recreate a protective skin layer that’s been lost and help your skin to hydrate itself from the inside out.
Other powerful ingredients and benefits you get from Phytoceramides:
Peptides – Increases skin elasticity and boosts collagen production
Ceramides – Protects your skin pollution, the sun and UV rays and stress
Antioxidants – Reduces and protects from free radical damage
So in a nutshell, here’s what you can expect when you take Skin Zen Phytoceramides:
- Get rid of wrinkles and fine lines
- Disappearing age and sun spots
- Disappearing under-eye bags
- Firmer, smoother skin overall
Are there any side effects?
Clinical trials have reported no known side effects when taking Phytoceramides. Some things to note are, as with many such supplements, pregnant women should consult a medical practitioner before taking them; Another is that anyone with a known rice allergy not consume. It is also recommended that, along with taking the pill, you drink plenty of water – essential for hydration – and engage in exercise, both of which are helpful in the quest for general health and healthy skin. The most recent research proving the effectiveness of Phytoceramides can be found in the below references.
A Clinical Review:
A 6-week study at Osaka City University consisted of 33 men and women with dry, rough skin. They used Phytoceramides in the form of soft gel capsules. The powerful combination of ingredients appeared to almost start taking action immediately. It appears that, when you take this supplement daily, your skin develops ability to moisturize itself. It also increases the production of collagen and decreases the production of elastase. This naturally leads to younger looking skin.
But that’s not all. It can also help protect your skin from harsh elements like pollution and the sun, as well as decrease the effects of stress on your skin. No side effects were noted during the study.
Additionally, Dr. Leif Rogers and Dr. Shirley Madhere, both highly acclaimed plastic surgeons, vouch for Phytoceramides’ ability to reduce wrinkles and fine lines.
- Rogers J, Harding C, Mayo A, Banks J, Rawlings A. Stratum corneum lipids: the effect of ageing and the seasons. Arch Dermatol Res. 1996 Nov;288(12):765-70.
- Denda M, Koyama J, Hori J, et al. Age- and sex-dependent change in stratum corneum sphingolipids. Arch Dermatol Res. 1993;285(7):415-7.
- Boireau-Adamezyk E, Baillet-Guffroy A, Stamatas GN. Age-dependent changes in stratum corneum barrier function. Skin Res Technol. 2014 Feb 12.
- Imokawa G, Abe A, Jin K, Higaki Y, Kawashima M, Hidano A. Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? J Invest Dermatol. 1991 Apr;96(4):523-6.
- Yarosh DB, Both D, Brown D. Liposomal ursolic acid (Merotaine) increases ceramides and collagen in human skin. Horm Res. 2000;54:318-21.
- Motta S, Monti M, Sesana S, Caputo R, Carelli S, Ghidoni R. Ceramide composition of the psoriatic scale. Biochim Biophys Acta. 1993 Sep 8;1182(2):147-51.
- Kim DS, Kim SY, Chung JH, Kim KH, Eun HC, Park KC. Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes. Cell Signal. 2002 Sep;14(9):779-85.
- Jeong HS, Choi HR, Yun HY, et al. Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase. Mol Cell Biochem. 2013 Mar;375(1-2):81-7.
- Coderch L, López O, de la Maza A, Parra JL. Ceramides and skin function. Am J Clin Dermatol. 2003;4(2):107-29.
- Rabionet M , Gorgas K, Sandhoff R. Ceramide synthesis in the epidermis. Biochim Biophys Acta. 2014 Mar;1841(3):422-34.
- Proksch E, Brandner JM, Jensen JM. The skin: an indispensable barrier. Exp Dermatol. 2008 Dec;17(12):1063-72.
- Choi MJ, Maibach HI. Role of ceramides in barrier function of healthy and diseased skin. Am J Clin Dermatol. 2005;6(4):215-23.
- Guenther GG, Edinger AL. A new take on ceramide: starving cells by cutting off the nutrient supply. Cell Cycle. 2009 Apr 15;8(8):1122-6.
- Guillou S, Ghabri S, Jannot C, Gaillard E, Lamour I, Boisnic S. The moisturizing effect of a wheat extract food supplement on women’s skin: a randomized, double-blind placebo-controlled trial. Int J Cosmet Sci. 2011 Apr;33(2):138-43.
- Boisnic S. Clinical evaluation of a hydrating food supplement: double blind randomized study versus placebo. HITEX. 2005.
- Takagi S, Tojo H, Tomita S, et al. Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function. J Clin Invest. 2003 Nov;112(9):1372-82.
- Leveque JL, Corcuff P, de Rigal J, Agache P. In vivo studies of the evolution of physical properties of the human skin with age. Int J Dermatol. 1984 Jun;23(5):322-9.
- Jennemann R, Rabionet M, Gorgas K, et al. Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet. 2012 Feb 1;21(3):586-608.
- Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-rpt0275-04-Udell-vol211.pdf. Accessed August 25, 2014.
- Yilmaz E, Borchert HH. Effect of lipid-containing, positively charged nanoemulsions on skin hydration, elasticity and erythema—an in vivo study. Int J Pharm. 2006 Jan 13;307(2):232-8.
- Asai S, Miyachi H. Evaluation of skin-moisturizing effects of oral or percutaneous use of plant ceramides. Rinsho Byori. 2007 Mar;55(3):209-15.
- Boisnic S, Beranger JY, Branchet MC. Cutaneous hydration evaluation after a vegetal ceramide-based cream application on normal human skin tissue model maintained alive, submitted to a dehydration model. HITEX;2003.
- Boisnic S, Beranger JY, Branchet MC. Anti-elastase and anti-radicalar effect of ceramides. Product Research Report. HITEX;2005.
- Kim DS, Kim SY, Moon SJ, Chung JH, Kim KH, Cho KH, et al. Ceramide inhibits cell proliferation through Akt/PKB inactivation and decreases melanin synthesis in Mel-Ab cells. Pigment Cell Res. 2001 Apr;14(2):110-5.
- Bielawski J, Pierce JS, Snider J, Rembiesa B, Szulc ZM, Bielawska A. Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods Mol Biol. 2009;579:443-67.
- Charkoudian N. Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin Proc. 2003 May;78(5):603-12.
- Webb AR . Who, what, where and when-influences on cutaneous vitamin D synthesis. Prog Biophys Mol Biol. 2006 Sep;92(1):17-25.
- Yu YD, Zhang YZ, Bi WD, Wu T. Functional sensory function recovery of random-pattern abdominal skin flap in the repair of fingertip skin defects. Exp Ther Med . 2013 Mar;5(3):830-4.
- Perry AD, Trafeli JP. Hand dermatitis: review of etiology, diagnosis, and treatment. J Am Board Fam Med 2009;22:325-30.
- Man MQ, Xin SJ, Song SP, Cho SY, Zhang XJ, Tu CX, et al. Variation of skin surface pH, sebum content and stratum corneum hydration with age and gender in a large Chinese population. Skin Pharmacol Physiol. 2009;22(4):190-9.
- Potts RO, Buras EM, Chrisman DA Jr. Changes with age in the moisture content of human skin. J Invest Dermatol. 1984 Jan;82(1):97-100.
- Available at: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0003734/. Accessed August 25, 2014.
- Del Rosso JQ, Levin J. The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin. J Clin Aesthet Dermatol. 2011 Sep;4(9):22-42.
- Yamamura T, Tezuka T. Change in sphingomyelinase activity in human epidermis during aging. J Dermatol Sci. 1990 Mar;1(2):79-83.
- Imokawa G. Lipid abnormalities in atopic dermatitis. J Am Acad Dermatol. 2001 Jul;45(1 Suppl):S29-32.
- Abeck D, Mempel M. Staphylococcus aureus colonization in atopic dermatitis and its therapeutic implications. Br J Dermatol. 1998 Dec;139 Suppl 53:13-6.
- Arikawa J, Ishibashi M, Kawashima M, Takagi Y, Ichikawa Y, Imokawa G. Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus. J Invest Dermatol. 2002 Aug;119(2):433-9.
- Fritz SA, Hogan PG, Hayek G, et al. Staphylococcus aureus colonization in children with community-associated Staphylococcus aureus skin infections and their household contacts. Arch Pediatr Adolesc Med. 2012 Jun 1;166(6):551-7.
- Lamagni TL, Neal S, Keshishian C, et al. Severe Streptococcus pyogenes infections, United Kingdom, 2003-2004. Emerg Infect Dis. 2008 Feb;14(2):202-9.
- Chamlin SL, Kao J, Frieden IJ, et al. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity. J Am Acad Dermatol. 2002 Aug;47(2):198-208.
- Novotny J, Hrabalek A, Vavrova K. Synthesis and structure-activity relationships of skin ceramides. Curr Med Chem. 2010;17(21):2301-24.
- Available at: http://www.oryza.co.jp/html/english/pdf/ceramide_clinical.pdf. Accessed August 25, 2014
- Goldstein AM, Abramovits W. Ceramides and the stratum corneum: structure, function, and new methods to promote repair. Int J Dermatol. 2003 Apr;42(4):256-9.
- Feingold KR, Elias PM. Role of lipids in the formation and maintenance of the cutaneous permeability barrier. Biochim Biophys Acta. 2014 Mar;1841(3):280-94.
- Harding CR. The stratum corneum: structure and function in health and disease. Dermatol Ther. 2004;17(Suppl):6-15.
Wong DJ, Chang H. Stem Book; 2009: Cambridge, MA. HY Skin tissue engineering.